Protein Details: Aquaporin PIP2-3

Protein ID

ICDB_Pro_0474

Protein Name

Aquaporin PIP2-3

Gene Name

PIP2-3; PIP2C; RD28; At2g37180; T2N18.6

Organism

Arabidopsis thaliana (Mouse-ear cress)

Length

285 amino acids

AlphaFoldDB

AF-P30302-F1-model_v4.pdb

Function

Water channel required to facilitate the transport of water across cell membrane; mercury-insensitive.

Sequence

MAKDVEGPDGFQTRDYEDPPPTPFFDAEELTKWSLYRAVIAEFVATLLFLYVTVLTVIGYKIQSDTKAGGVDCGGVGILGIAWAFGGMIFILVYCTAGISGGHINPAVTFGLFLARKVSLIRAVLYMVAQCLGAICGVGFVKAFQSSHYVNYGGGANFLADGYNTGTGLAAEIIGTFVLVYTVFSATDPKRNARDSHVPVLAPLPIGFAVFMVHLATIPITGTGINPARSFGAAVIFNKSKPWDDHWIFWVGPFIGATIAAFYHQFVLRASGSKSLGSFRSAANV

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

Widely expressed; except in seeds.

DOI ID

10.1038/45471; 10.1111/tpj.13415; 10.1126/science.1088305; 10.1104/pp.106.4.1325; 10.1186/gb-2001-3-1-research0001

RefSeq

NP_181255.1